Various analytical methods are relied upon in DNA sequencing (Sanger, NGS, nanopore, pyrosequencing etc.), which aims to determine the sequence of nucleotides encoding a given gene.
A common point to all these methods is their extensive use of low flows, which require a high level of precision and control. Any instrument inaccuracy in flow delivery can be quite costly to end users in terms of samples and time, as well as to the manufacturers who provide maintenance services.